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Pin ItCalorie restriction (CR) and a ketogenic diet (KD) target the same molecular pathways that are also targeted individually by drugs to improve cancer treatment outcomes. Arrows indicate activation, truncated lines inhibition. Carbohydrate (CHO) restriction up-regulates fatty acid oxidation and ketogenesis (beneficial for normal tissues) and impairs glycolysis and glutaminolysis (detrimental to tumor cells). Full study here.Health Impact News Editor Comments:One of the truly exciting new frontiers in nutrition therapy is the study of the high-fat low-carb ketogenic diet, especially in relation to preventing and curing cancer. The ketogenic diet as a therapeutic diet is not new.

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Study: Intermittent Fasting and Ketogenic Diet Effective in Cancer …

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The Impact of Nutrition on Autoimmune Disease – Part 3 8 Comments Thursday, November 7th, 2013 Written by: Matt Baran-MickleBe sure to check out Part 1 and Part 2Metabolism and ImmunityThe obesity epidemic is widely recognized, and while the precise causes are not entirely clear, the presence of excessive nutrient intake and subsequent systemic metabolic dysfunction is not controversial. Obesity is frequently accompanied by a variety of conditions that are collectively referred to as the metabolic syndrome, including high plasma glucose, high plasma fatty acids/triglycerides, hypertension, and insulin resistance; immunological alterations in obesity are increasingly recognized as well, and the presence of chronic inflammation is a hallmark of the condition.(image: Kanneganti & Dixit, 2012)These immunological alterations are quite pronounced, and include the accumulation of activated lymphocytes and innate cells in obese fat tissue, and a depletion of Treg cells, as well as mucosal barrier disruption and dysbiosis. Recent work has begun to unravel the interrelation of immunity and metabolism, and provides some intriguing evidence for our developing understanding of autoimmune disease.Like every other cell, leukocytes require energy and metabolic substrate to maintain normal cellular function, and to divide and proliferate.

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Robb Wolf – Impact of Nutrition on Autoimmune Disease – Part 3

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21 Feb 2012 Intermittent Fasting and Brain Health Permalink|View Comments (5)|Post Comment|Share|Posted by ReasonLoading…Via the Guardian: “Fasting for regular periods could help protect the brain against degenerative illnesses … Researchers [had] found evidence which shows that periods of stopping virtually all food intake for one or two days a week could protect the brain against some of the worst effects of Alzheimer’s, Parkinson’s and other ailments. … Reducing your calorie intake could help your brain, but doing so by cutting your intake of food is not likely to be the best method of triggering this protection. It is likely to be better to go on intermittent bouts of fasting, in which you eat hardly anything at all, and then have periods when you eat as much as you want.

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Intermittent Fasting and Brain Health – Fight Aging!

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